Basic Molecular Information

Basic Information

DICL ID
DICL_CP_0336765
PubChem CID
N/A (Not available)
Molecular Formula
C19H26N4O
Molecular Weight
326.444 g/mol
Synonyms/Alias
N/A (Not available)
InChI Key
RFVARTJEHKYUKS-UHFFFAOYSA-N
InChI
InChI=1S/C19H26N4O/c1-14-8-9-17(12-20-14)11-19(24)21-18-10-15(2)22-23(18)13-16-6-4-3-5-7-16/h8-10,12...
IUPAC Name
N-(1-(cyclohexylmethyl)-3-methyl-1H-pyrazol-5-yl)-2-(6-methylpyridin-3-yl)acetamide
CAS Number
N/A (Not available)

Structure Information

Chemical Structure Visualization

SMILES Notation
2D Molecular Drawing
Carbon (C)
Hydrogen (H)
Oxygen (O)
Nitrogen (N)
Sulfur (S)
SDF

24 26 0 0 0 0 0 0 0 0999 V2000
-6.6661 -1.9113 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-5.5695 -0.8879 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
-5.9076 0...

Experimental Data

Activity Data

Target Ion Channel
Inward rectifier potassium channel 2
Uniprot Accession Number
Function
Inhibitor
Species
Rattus norvegicus (Rat)
IC50
IC50: 3890 nM
EC50
N/A (Not available)
Ki
N/A (Not available)
Kd
N/A (Not available)
Inhibition
N/A (Not available)

Experimental Conditions

pH
pH 7.2
Holding Potential
Not specified
Temperature
37 °C
Test Method
Flux assay (Thallium ion)
Test Species
Not specified

Binding Information

Binding Site
Not specified
Binding Site Residue
Not specified

Disease Information

Related Disease
Not specified

References

URL
N/A (Not available)
PMID
Patent
N/A (Not available)

Computed Properties

Heavy Atom Count
24
Rotatable Bonds
5
logP
3.6564
Complexity
94.8467
TPSA (Ų)
59.81
H-Bond Donors
1
H-Bond Acceptors
4
Ring Count
3
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